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Transpersonal perspectives on the meaningfulness of being human, and especially the significance of subtle energy teachings, necessitate a rethinking of the notion of sexuality, beyond definitions in terms of sex acts, biological endowments, or perhaps even the complex fantasia of desire. This redefining of the erotic dimension of human life leads both to appreciation of healing as inherently sexual and to understanding how the processes of transmutation by the forces of subtle energies profoundly differ from the transformations that representation of thoughts, feelings, and wishes may undergo. Cognitive access (including that of reflective selfconsciousness) to these forces is inevitably limited and necessarily distorted. In this context, it is suggested that the esoteric traditions of mystical sexuality, including the teachings of authentic tantric practice, be reconsidered and appreciated for their transpersonal dimension.